Advantages and disadvantages of friability test

The friability testing is a method that is used to determine the physical strength of tablets (compressed/uncoated) exposed to mechanical shocks and attraction, let's check their some advantages and disadvantages.

The design, quality control, and post-formulation of tablet dosage form include comprehensive assessments and evaluations of the chemical, physical, and bioavailability properties of the tablet. The tablets are subject to different tests (post-production) such as friability, hardness, and dissolution as per the standard procedure of pharmacopoeias such as USP, BP, and IP. Friability testing is a method that is performed using the friability tester and that is employed to determine the physical strength of uncoated and compressed tablets when exposed to mechanical shock.

Advantages of friability testing:

• The Friability test is commonly used in the pharmaceutical industries or research and it tells us how the tablets have durability during packing processes and transit.
• It helps in the consistency and reproducibility of product in batch-to-batch production.
• It determines the quality of pharmaceutical products.
• As per the standards of pharmacopoeia such as USP, BP, and IP it is used in the research and development as a regulatory perspective.
• There is no need for repetition; a sample of 10/20 tablets is checked at a time so that results are given at once.
• It is an automated process and is easy to use so there is no need for an expert to handle it.
• The most advanced apparatus provides automatic pre-set count stops, balance interface, and a printing facility.

Disadvantages of friability testing:

• Friability can be affected by several factors such as moisture content of tablet granules, humidity, and hardness.
• Acrylic drums have to be handled carefully due to their fragility.
• It needs to be frequently calibrated such as drum alignment, counting, etc.
• It works only for compressed or uncoated tablets.
• The process is slow it takes time to complete.

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