Wednesday, May 5, 2021

Difference between pharmaceutical paste and gel

Appearance and texture is the major difference between paste and gel, the paste is a water-based formulation, it contains finely powdered medicaments, whereas gel is generally alcohol or water-based formulation are transparent or translucent.

Pharmaceutical Dosage forms are the means by which active pharmaceutical ingredients are delivered to the specific site of the body. Dosage forms come in different types, based on the physical form they are solid, liquid, semisolid, and gaseous dosage forms, and based on routes of drug administration they are oral, parenteral, buccal, ocular, otic, and topical route. 
Examples of dosage forms are tablet, capsule, granules, cream, ointment, emulsion, suspension, solution, syrup, liniment, inhaler, and aerosol, etc.

Topical preparations are localized drug delivery systems for local delivery of medication via skin to treat the cutaneous disorder. The formulations are available in different forms such as ointment, cream, paste, gel, lotion, jelly, foam, suspension, emulsion, powder, patches, and gauzes, etc. they are used for external applications as cosmetic and medicinal.

Pastes:

Pharmaceutical pastes are thick semi-solid dosage forms that contain one or more drug substances with excipients intended for application to the skin, mucous membranes, or oral cavity. They are mostly water-based products and prepared by a large amount of finely divided powdered drug that is incorporated into a suitable base vehicle.

Gels:

Gels are semi-solid formulations, consisting of suspensions made up of small inorganic particles or large organic molecules interpenetrated by a liquid. It is a transparent jelly-like product that liquefies on the skin to leave a thin film of an active ingredient.

Paste vs Gel:

  • The paste is less greasy, not transparent or translucent, whereas gel is non-greasy, transparent, or translucent.
  • The paste cannot be used as lubricants, while gels can be used as lubricants.
  • The paste contains a high amount of fine powder, while gel formulation does not contain finely powdered drugs.
  • The paste does not provide a good cooling effect, while the gel provides a good cooling effect.
  • The paste is absorbed slowly compared to gel, while the gel is absorbed more rapidly by the skin.
  • Gelatin or carbohydrates are not used in the manufacture of paste, while used in the formulation of gel.
  • The paste may be not use on hair, while gel can be applied to hair for cosmetic purposes.
  • Pastes are more suitable for dry hair, while gels are more suitable for wet hair.
Difference between paste and gel

Similarity between gel and paste:

The gel and paste both are semisolid dosage forms intended for the topical application intended for topical use in both cosmetics and pharmaceutical products.

Commonly asked questions on gel and paste are as follows.

What is the difference between hair gel and hair cream? 
Hair gel is a water-based product, whereas hair paste is a wax-based product. Hair gel and hair cream both are hair styling products, although creams are not as popular as gels.

What is a major difference between toothpaste and gel?
The taste, appearance, and texture are the major difference between toothpaste and gel.


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