The major difference between coated and uncoated tablets is that the coated tablets are designed to control the release profile of the drug, masking odor and taste, whereas uncoated tablets are designed to provide rapid disintegration in the gastric fluid of the stomach, and after the compression of these types of tablets no special process is required.
Solid dosage formulations such as tablets, capsules, granules, sachets, powders are the most important dosage forms for pharmaceuticals because of their significant advantages and applications.
The tablet is one of the most commonly prescribed and used for medicine. It is unit, solid dosage form of medicine, which contains one or more active pharmaceutical ingredients (API) for oral administration, hence it is also called oral solid dosage form. The tablets are made from granulated or powdered materials that are strongly pressed together during manufacturing to form a hardened tablet.
Uncoated tablets:
The uncoated tablet is a single layer or multi-layer of formulation that contains the drugs or medicines and excipients simultaneously without any coating. In general, it is a single compression of granules or multi-layer tablets consisting of parallel layers prepared by compression of granules of various compositions. These types of pills do not require additional processing after compression. The majority of uncoated tablets are made in such a way any substances added are not intended expressly to alter the release rate or dissolution rate of their active ingredients. Soluble tablets, dispersible tablets, and effervescent tablets are some types of uncoated tablets.
Coated tablets:
Coated tablets are covered with an extra thin layer to manage their release rate, to mask unpleasant taste and odor, and to keep them from external influences, such as light, moisture, heat, and bacteria. Coated tablets are smooth, colorful, shiny, and often become tasteless and easier to swallow. The different types of tablet coatings apply to different types of tablets according to requirements. The material used for coating is usually applied as a solution or suspension that does not affect the quality of the drug and does not have side effects. Sugar-coating, film-coating, and enteric coating are widely used in the pharmaceutical industries.
Commonly asked questions on pharmaceutical dosage forms are as follows.
What are the steps involved in tablet coatings?
The steps involved in tablet coatings are sealing of tablet core, sub-coating, smoothing, coloring, polishing, and printing.
What are the different types of pharmaceutical tablets?
Coated tablets, uncoated tablets, dispersible tablets, effervescent tablets, modified-release tablets, enteric-coated tablets, prolonged-release tablets, soluble tablets, chewable tablets, buccal and sublingual tablets are the types of pharmaceutical tablets.
What are the different types of the granulation process?
There are two types of granulation techniques such as dry granulation and wet granulation.
What are the advantages of tablets?
The major advantages of tablets have stable dose, dose accuracy, high precision, lowest variability, and most stable in chemical, physical, and microbiological properties.
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How to identify coated and uncoted tablet in the medicine
ReplyDeleteCoated tablets are generally shiny and smooth, while uncoated tablets are rougher.
DeleteHope your query is resolved.
Good knowledge 👍👌
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