There is the use of buffer solution is essential in pharmaceutical process and analysis study. The buffer solution has base and acid. It can be a strong acid with a weak base, or a weak base with a strong acid used to keep the right pH balance.
Here are mentions some Factors influencing the pH of Buffer Solutions are as follows.
- The temperature change varies the pH of a buffer solution, every buffer can influence differently. For example the pH of sodium borate- boric acid buffer solution reduces with temperature, while the pH of acetate buffer rises with temperature.
- By adding neutral salts to the buffer solution, the pH of the solution can be changed due to the change in ionic strength.
- Dilution of the buffer solution also modifies the pH value since as changed in ionic strength.
- The activity of hydronium ion, and the activity of ionized species that changes the pH of the buffer solution.
- In addition, the amount of the change compared to the basic buffer is relatively small for the acidic buffer.
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