Granulation, the process of particle expansion by the agglomeration method, forms of drug dosage, is one of the most important unit operations for the manufacturing of most tablets and capsules. The granulation process converts fine powder into dust-free, free-flowing granules which are easy to compress.
However, due to the high quality of granules formed in the case of material uniformity and physical-chemical properties such as bulk density, granulation size, moisture, hardness, compressibility etc. granulation faces many challenges, by means of chemical and physical stability of the drug.
Granulation processes are divided into two types: Wet granulation and Dry granulation, in wet granulation the process which uses a liquid and dry granulation which uses solid.
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