Tuesday, February 7, 2023

Applications of complexometric titrations

Complexometric titrations are specifically used to determine the mixtures of different metal ions in solution. The endpoint of the titration is usually identified using an indicator that causes a color change.

Titration is a specific laboratory method for determining the concentration of an unknown analyte, based on the goals and procedures it has 4 types, acid-base, redox, precipitation, and complexometric titration.

Complexometric titration, which is also called chelatometry, is a method of volumetric analysis in which a colored complex is used to detect the endpoint of the reaction. It is performed using a chelating agent, such as ethylenediaminetetraacetic acid (EDTA).

The EDTA reacts with the metal ions in the sample to form complexes, which can then be titrated with standard acid. Measuring the endpoint of the titration allows the concentration of the metal ion present in the sample to be determined.

Direct titration, back titration, replacement titration, and indirect titration methods are some of the numerous methods of complexometric titration.

Applications of complexometric titration:

  • The major application of complexometric titration is that it is used to measure the amount of metal ions present in sample solutions.
  • This method is used to determine the various complexes of magnesium and calcium that are present in water and which act as a hardening agent of water.
  • It is used to analyze urine and blood samples, etc, in the field of biological analysis.
  • It is possible to use complexometric titration to test for the presence of calcium, magnesium, and other metals in food products such as milk, orange juice, vegetables, etc.
  • In the pharmaceutical industry, complexometric titration is often used to determine the concentration of a metal present in a pharmaceutical dosage form (Drug).
  • In analytical chemistry, it is used in the process of performing assays.
  • Titanium dioxide content in cosmetic products can be determined through the use of complexometric titrations.
  • In the field of environmental analysis, complexometric titrations are used to determine bad metals.
  • Complexometric titrations can also be used to determine the concentration of a weak acid or a weak base in a solution. The weak acid or base concentration can then be determined by measuring the amount of strong acid or base used in the titration.


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