Different types of coatings are required according to the design and properties of the tablet, and it has many advantages and disadvantages, let's check it out.
The tablet is a solid dosage form which consists of a mixture of active pharmaceutical ingredients and excipients, usually in powder form, compressed or compacted into a solid. The tablet is one of the most prescribed and preferred dosage forms as it has several advantages compared with other types of dosage forms. It is possible to formulate almost all drug molecules in a tablet and the manufacturing process of tablets is very simple and very versatile.
The coating is a process of adding an effectively dry, external layer of coating material to the surface of a dosage form to achieve specific advantages. Tablet coating is an important step involved in the manufacturing of tablets and it can be applied to a wide range of tablets. Tablets are usually coated with a coating solution consisting of a mixture of pigments, polymers, and excipients that are dissolved in water or an organic solvent to form a coating solution, subsequently sprayed in a pan-coater onto the tablets and dried by continuous hot air supply until a dry coating film is formed.
Advantages of tablet coating:
- The major advantage of tablet coating is that can control the release rate of the drug, and protects from the unpleasant taste and odor of the medicine.
- The coating gives a smooth finish to the product makes it easy to swallow.
- The coating enhances product acceptance and the appearance of the tablet.
- The coating can reduce the frequency of dosing by providing controlled, sustained release.
- It maintains physical or chemical drug integrity by protecting against humidity, heat, and temperature.
- This protects the medicine from being disintegrated into acidic conditions of the stomach until reaching the intestine.
- It can maintain the shape of the tablet and makes it tamper-resistant.
Disadvantages of tablet coating:
- The major disadvantage of tablet coating is that the coating process is tedious and time-consuming, which makes it expensive.
- The pharmacodynamic properties of the formulation can interfere with the tablet coating.
- The technique may often lead to several defects in the coating, such as chipping, cracks, etc.
- The coating process is complex compared to other processes and therefore a trained person is required to handle this process.
Commonly asked questions on dosage form are as follows.
What are the different types of tablet coating?
Several types of tablet coating are used in pharmaceutical manufacturing according to the properties and nature of tablets which are sugar coating, film coating, enteric coating, controlled release coating, specialized coating, compressed coating, electrostatic coating, dip coating, and vacuum film coating
What are the processes involved in the coating?
Loading/dispensing, warming, spraying, drying, cooling and unloading are the processes involved in the coating.
How many types of capsule filling machines are there?
Manual /hand operated capsule filling machine, semi-automatic capsule filling machine, and automatic capsule filling machine are three types of capsule filling machines.
What is the difference between tablets and capsules?
The major difference between tablets and capsules is that the capsules are the form of the medication we can't cut into two as drugs are enclosed in a gelatin shell whereas tablet is a form of compressed powder we can cut into two.
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