The major difference between dissolution and dissociation is that dissociation is a common method for the separation of ionic compounds into smaller ions, which is normally in a reversible manner whereas dissolving or dissolution is the process in which ionic crystals break down into ions in water.
Dissolution:
The term dissolution is used when ionic compounds dissolve in water, in which the ions that were previously present in the solid-state when added to water. e.g. NaCl.
Dissolution means, the way of solid dosage form toward forming or dissolving in a medium or solution. While dissolution occurs, then it dissociates the solute into molecules or ions, and every molecule or ion is bounded by the solvent molecules. The interaction amongst the particles of solute and molecules of solvent is called salvation.
The dissolution of the oral solid dosage form like a tablet, capsule, and caplets, etc. perform on the dissolution apparatus. It is available in different types such as USP dissolution apparatus, BP dissolution apparatus, and IP dissolution apparatus.
Dissociation:
The separation process of the solute ions, while it is added to the solvent, is known as dissociation. It occurs while the attraction amongst the ions of solute is far weak compared to molecules of the solvent and ions of the solute, in such case, the solvent encloses the ion of solute and drags them away from each other.
Organic compounds such as glucose and sugars, which are molecular compounds, dissolve in water and form H-bonds with water, causing their molecules to dissociate from each other, breaking their solid-state structure.
Commonly asked questions are as follows
What are the factors that affecting solubility?
The concentration of the solute, the temperature of the system, pressure of the system, and polarity of the solute are the factors that affect solubility.
What is a disintegration test?
Disintegration is a physical process in which small particles of a tablet or granulated particle are mechanically fragmented.
What is miscibility in chemistry?
Miscibility is the property of two substances to combine/mix in all proportions and form a homogeneous solution is known as miscibility.
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