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Wednesday, April 21, 2021

Difference between syrup and solution

The major difference between solution and syrup is that a solution is a homogeneous mixture formed by dissolving one or more active ingredients, whereas syrup is a viscous oral liquid consisting primarily of sugar or any other sweetening agent.
Dosage forms are intended to deliver the active pharmaceutical ingredient (API) at the site of action within the body. They come in many types depending on the mode/route of administration. Based on the physical form they are liquid, solid, semisolid, and gaseous dosage forms, and based on route they are oral, topical, inhalation, and parenteral route of drug administration. The most commonly used dosage forms include tablets, capsules, granules, syrup, suspensions, elixir, creams, ointments, and injections, etc.

Liquid dosage forms provide rapid and high absorption of soluble drug products hence are one of the oldest dosage forms used to treat various diseases. It can be administered orally, parenterally, or topically. It is especially used for patients who have difficulty swallowing, such as children and elders.
E.g. Syrups, solutions, ear drops, ear drops, lotion, elixirs, and parenteral preparations, etc.

What is syrup in pharmacy?

Liquid syrups are one of the dosage forms that contain a concentrated solution of sugar mixed in water or other aqueous liquid. The syrup is a saturated solution in which drugs dissolve. Some syrup is less viscous, while some are more viscous which is dependent upon the concentration of sweeteners used in the formulation.
It is an oral suspension in liquid form that is used as a vehicle for the drug. Simple syrup, medicated syrup, and flavored syrup are the three types of syrups preferably suitable for pediatric use. The syrup should be stored in a tightly-closed container and in a cool, dry place after use to preserve them.

What is a solution in pharmacy?

Pharmaceutical solutions are liquid formulations in which one or more solutes with excipients have been dissolved in a suitable solvent or miscible solvent mixture. Pharmaceutical solutions are homogeneous, and they can be classified as oral, otic, ophthalmic, or topical, as well as injections, which are sterile and pyrogen-free solutions intended for parenteral administration. Vehicle solutions are classified as aqueous solutions and non-aqueous solutions.

Difference between syrup and solution:

  • The pharmaceutical syrup is intended to use for oral administration while solutions are used for many routes of administration, including oral, rectal, otic, parenteral, and ophthalmic.
  • The syrup can be opaque and cloudy in appearance, while the solution can clear in appearance.
  • Because of the high sugar content, the syrup may not be appropriate for diabetic patients, while the solution is suitable for all types of patients.
  • The oral syrup is always sweet while the oral solution is not.
  • The syrup scatters the beam of light, while the solution is transparent does not disperse the ray of light.
  • The syrup may take more time to filter as it is more viscous, whereas the solution can rapidly be filtered through the filter paper.

Commonly asked questions on syrup and suspension are as follows.

Is syrup a suspension or colloid?
The syrup is not a colloid, it is a suspension solution. Since a colloid is an insoluble microscopic particulate suspended in a solvent, the mixture contains both liquid and solid components.

What is the similarity between syrup and solution?
The major similarity between syrup and solution is that pharmaceutical syrups and solutions are the mixtures of solutes in which the drug particles are also completely dissolved in the solvent.

What are the examples of solutions?
In a solution, all the components appear as a single phase. Common examples of solutions are the sugar dissolved in water, salt dissolved in water, juice, soda water, etc.


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