The tablet coating is particularly formulated to regulate the rate or speed of tablet dissolution where and how the active pharmaceutical ingredients (API) are to be absorbed after ingestion in the body.
Powder, capsules, tablets, liquids, suspensions, injections are methods of delivering medication, of which tablets and capsules are the most commonly prescribed and used forms of medicine that comes with different types. The challenge for manufacturers of medication is to turn a valuable natural or chemical compound into an effective and safe dosage form for the consumption of patients. They should go where they need to go to do their work without harming other parts of the body.
Tablet coating is an important step involved used by the pharmaceutical industries in the manufacturing of tablets with delayed release, sustained, and controlled release profiles. It is most important that the coating should be uniform and under stress, it should not crack. Therefore, different methods were developed for applying the coating on the surface of the tablet.
Generally, when the tablets are agitated in a pan, fluid bed, etc., the coating solutions are sprayed on the uncoated tablets. A thin film that sticks to each tablet is formed when the solution is applied. Through passing the air over the surface of the tumbling pans, the liquid portion of the coating solution is then evaporated. The coating can either be formed by a single application or, by the use of several spraying cycles, may be established in layers.
The tablets are coated for the following reasons.
- To mask the odor and taste of the medicines and excipients used in the formulation
- To prevent the degradation of tablet or capsule in the stomach and make them usable in the intestine, using cellulose or other material coatings
- To control the site of drug release
- To maintain the physical or chemical integrity of the drug (API)
- To maintain the shape of the tablet
- To increase the appearance and acceptance of the product
- To provide delayed release of the drug (medication)
- To provide sustained release, controlled release, or decreasing the drug dosing frequency
Commonly asked questions of tablet coatings are as follows.
What are the different types of tablet coating?
The different types of tablet coating such as sugar-coated tablets, film-coated tablets, gelatin-coated tablets, enteric-coated tablets, compression coating tablets, and some other types of coatings
Why tablets are enteric-coated?
The enteric-coated tablet is made from more than one drug (API) and can cause stomach problems, therefore, to prevent disperse of the tablet in the stomach, and to release the drugs in the intestine the tablet has enteric-coated.
What are the advantages of a tablet-coating?
The tablet coating has several advantages, like masking odor, taste, and color of the drug, providing physical and chemical protection to the drug, protecting the drug from the gastric environment.
What are the types of dosage forms in pharmaceutics?
Pharmaceutical dosage forms are categorized according to physical characteristics into four categories, such as solid dosage forms, semi-solid dosage forms liquid dosage forms, and gaseous dosage forms.
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