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Saturday, May 12, 2018

Precision

There are three parameters in the precision study: Repeatability, Intraday Precision, and Interday Precision. In the repeatability study spikes the same sample solution six times and the result should have RSD ≤ 1.0 %.
In intraday precision inject the sample of three different concentrations and should have RSD ≤ 2 %. And In Interday inject the same sample of three different concentrations within 2 to 3 days at the same conditions and should have RSD ≤ 2 %.

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Accuracy

Specificity
Limit of Detection (LOD)
Limit of Quantitation (LOQ)
Linearity
Range
Robustness
Rougdness
Method Validation

pKa Value
Retention Time
Factor Affecting Retention Time in HPLC
Resolution in Chromatography
Dead Volume
Capacity Factor

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